BDBM15186 4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cyclopenta[b]pyridin-5-ylidene]methyl}furan-2-yl)-2-chlorobenzoic acid::cid_1776570::compound 1::compound 6065233

SMILES Cc1c(C#N)c(N)[nH]c2c(C#N)c(=C)c(=Cc3ccc(o3)-c3ccc(C(O)=O)c(Cl)c3)c12

InChI Key InChIKey=YQXKFAZZJMIBIB-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15186   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
The Burnham Institute

LigandPNGBDBM15186(4-(5-{[(5E)-2-amino-3,7-dicyano-4,6-dimethyl-5H-cy...)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.12kcal/mole IC50:  2.60E+3nMpH: 7.5 T: 2°CAssay Description:The Z-LYTE assay (Invitrogen Corporation) employs a FRET-based, coupled-enzyme format and is based on the differential sensitivity of phosphorylated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed